Curriculum Vitae (pdf)
    
      Cell Kinetics Laboratory

     
     

   


CONTACT


Foundation for Research and Technology – HELLAS (FORTH)
Institute of Applied and Computational Mathematics (IACM)
P.O. Box 1385
Vassilika Vouton
711 10 Heraklion Crete
HELLAS (Greece)

Telephone Number: +30-28210-49321
Fax Number: +30-2810-391801
E-mail Address:

EDUCATION


Doctor of Philosophy
(1998 - 2003)
Applied Physiology (major)
Department of Kinesiology, The University of Toledo, Toledo, OH, USA
Advisor:  Dr. Francis X. Pizza
Dissertation:  "Myotube-derived neutrophil chemoattractants:  Effects of mechanical strain and injury"

Molecular/Cell Biology (minor)
Department of Pathology, Health Science Campus, The University of Toledo, Toledo, OH, USA
Supervisor:  Dr. William T. Gunning, III

Master of Science
(1996 -1998)
Exercise Science
Department of Health Promotion and Human Performance (later Kinesiology), The University of Toledo, Toledo, OH, USA
Advisor:  Dr. Fredrick F. Andres
Thesis:  "Effects of a single bout of moderate swimming and running on arterial blood pressure during exercise and recovery"

Bachelor of Science
(1992-1996)
Exercise Science and Physical Education
Department of Physical Education and Exercise Science, Democritus University of Thrace, Komotini, HELLAS
Thesis Supervisor:  Dr. Panayiotis Antoniou 
Thesis (with honors): "Effects of heredity on hemodynamics of pre-adolescent swimmers during maximal exercise and recovery"

Physical Education (exchange student; 1995)
Sports, Health, Coaching and Physical Education, College of St. Mark & St. John (Marjon), Plymouth, UK
Supervisor: Dr. Harry Richardson


Diploma
(1991)
Palamaiki Scholi - 1st Geniko Lykeio (High School), Major: Ancient Hellenic Literature, Latin, and History, Messolonghi, HELLAS.



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PROFESSIONAL EXPERIENCE



2010 - Current
Adjunct Assistant Professor, University of Maryland University College-Europe, European Headquarters: Heidelberg, Germany. 

2006 - Current
Research Scientist, Institute of Applied and Computational Mathematics, Foundation for Research and Technology-HELLAS, Heraklion, Crete, HELLAS

2005 - 2006 Post-Doctoral Fellow, IACM-FORTH, Heraklion, Crete, HELLAS

2003 - 2005
Post-Doctoral Fellow, Department of Pharmacology - Dr. Pavlath Lab, Emory University School of Medicine, Atlanta, GA, USA

1996 - 2003
Graduate Teaching/Research Assistant, Department of Kinesiology, The University of Toledo, Toledo, OH, USA

1997 - 2003
Research Assistant (volunteer), Department of Pharmacology (former), Health Science Campus, The University of Toledo, Toledo, OH, USA

1996 - 1997
Sports Instructor, Division of Continuing Education, The University of Toledo, Toledo, OH, USA

1995 - 1996
Undergraduate Research Assistant (volunteer), Applied Physiology Laboratory, Department of Physical Education and Exercise Science, Democritus University of Thrace, Komotini, HELLAS


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ACADEMIC HONORS AND AWARDS



2002 - 2003
Outstanding Doctoral Student Award
Department of Kinesiology, The University of Toledo, Toledo, OH, USA

1997 - 1998
Outstanding Graduate Student Award
Department of Health Promotion and Human Performance, The University of Toledo, Toledo, OH, USA


1995 - 1996
Class Valedictorian, Department of Physical Education and Exercise Science, Democritus University of Thrace, Komotini, HELLAS

1995 - 1996
Outstanding Student Fellowship, Foundation of State Scholarships, HELLAS

1994 - 1995
"Erasmus Exchange Student Scholarship, EUROPEAN UNION (EU)

1993 - 1994
Outstanding Student Fellowship (ranked 1st in class), Foundation of State Scholarships, HELLAS

1992 - 1993
Outstanding Student Fellowship (ranked 1st in class), Foundation of State Scholarships, HELLAS


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TEACHING EXPERIENCE



Graduate Courses


MATH131
Biomathematics I - Population Biology: "Our internal microworld in kinesis: a special glance on cancer cell metastasis" lecture (Technical University of Crete)
.

PHARM/BCDB
Supervise doctoral student research (Emory)

PHARM 531
Introduction to Pharmacology: "Excitation-Contraction Coupling" (Emory)

KINE 6/8550
Advanced Laboratory Techniques in Exercise Physiology (Laboratory; UT)

KINE 6/8550 Laboratory Techniques in Exercise Physiology (Laboratory; UT)

Undergraduate Courses


BIOL 103
Introduction to Biology (UMUC-Europe)

KINE 3530
Applied Exercise Physiology Laboratory (UT)

KINE 2540
Human Physiology Laboratory (UT)

KINE 1080 Health and Exercise (Lecture and Laboratory; UT)


Other Classes


KINE 1/2000
Sports training/coaching (swimming, water polo, volleyball, tennis; UT)

Cont. Education
Swimming Instructor for infants, toddlers and pre-adolescent children (UT)

Extracurricular
Swimming Instructor (Democritus University of Thrace)


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RESEARCH GRANT



Principal Investigator, “Mechanotaxis in the guidance of cancer metastasis”
Marie Curie International Reintegration Grant (MCIRG), European Commission FP6, Marie Curie Actions

Foundation of Research and Technology-HELLAS, Institute of Applied and Computational Mathematics, Heraklion, Crete, HELLAS, 2006-2009.


                                          Top PUBLICATIONS



Mylona E., Z.H. Dailiana, X. Trepat, and M.G. Lagoudakis. Substrate Rigidity Dictates Phenotype, Survival, and Mechanics of Primary Human Osteosarcoma Cells, 6th European Symposium on Biomedical Engineering Proceedings, 2008.


Jetzek F., E. Mylona, and D. Manoussaki. Prediction of potential locations of focal adhesions on the contour of adherent cells. Fifth IEEE International Symposium on Biomedical Imaging Proceedings, 2008.


Stéphanou A., E. Mylona, M. Chaplain, and P. Tracqui. A computational model of cell migration coupling the growth of focal adhesions with oscillatory cell protrusions J. Theor Bio. 253(4): 701-16, 2008.

Mylona, E.
,
K. A. Jones, S.T. Mills, and G.K. Pavlath. CD44 regulates myoblast migration and differentiation J. Cell. Physiol., 209(2): 314-321, 2006
.

Tsivitse, S.K., E. Mylona, J.M. Peterson, W.T. Gunning, and F.X. Pizza.
Mechanical loading and injury induce human myotubes to release neutrophil chemoattractants. Amer. J. Physiol. Cell Physiol. 288 (3): C721-9, 2005  

McLoughlin, T.J., E. Mylona, T.A. Hornberger, K.A. Esser, F.X. Pizza. Inflammatory cells in rat skeletal muscle are elevated after electrically stimulated contractions. J. Appl. Physiol. 94(3): 876-82, 2003 

Peterson, J.M., T.A. Trappe, E. Mylona, F. White, C.P. Lambert, W.J. Evans, F.X. Pizza. Ibuprofen and acetaminophen: effect on muscle inflammation after eccentric exercise. Med. Sci. Sports Exerc. 35(6): 892-6, 2003.

Tsivitse, S.K., T.J. McLoughlin, J.M. Peterson, E. Mylona, S.J. McGregor, and F. X. Pizza. Downhill running in rats: influence on neutrophils, macrophages, and MyoD+ cells in skeletal muscle. Eur. J. Appl. Physiol. 90(5-6): 633-8, 2003.

Mylona, E., M. Fahlman, A.L. Morgan, D.J. Boardley, and S.K. Tsivitse. S-IgA following a single bout of exercise: Effects of fitness level and ambient temperature. Int. J. Sports Med., 23(6): 453-456, 2002.


Frenette, J., M. St-Pierre, C. H. Cote, E. Mylona, and F. X. Pizza. Muscle impairment occurs rapidly and precedes inflammatory cell accumulation after mechanical loading. Amer. J. Physiol., 282: R351-R357, 2002.

Lambert, C.P., M.G. Flynn, W.A. Braun, and E. Mylona. Influence of acute submaximal exercise on T-lymphocyte suppressor cell function in healthy young men. Eur. J. Appl. Phys., 82 (1/2): 151-154, 2000.

Braun, W.A., M.G. Flynn, D.E. Jacks, T. McLoughlin, J. Sowash, C.P. Lambert, and E. Mylona. Indomethacin does not influence natural cell-mediated cytotoxicity response to endurance exercise. J. Appl. Phys., 87: 2237-2243, 1999.


                                          Top ABSTRACT PUBLICATIONS



Mylona E., Alexopoulos L.G., Chairakaki K., Melas I. Substrate rigidity alters the secreted protein profile and chemotaxis response of fibrosarcoma cells. 444th Wilhelm and Else Heraeus Seminar on Cell Mechanics and 3rd European Meeting on Cell Mechanics Proceedings, Bad Honnef, GERMANY, October 2009.

Dailiana, ZH; E. Mylona, X. Trepat, M.G. Lagoudakis, and M. Ioannou. Primary human osteosarcoma cell responses to alterations in substrate rigidity. Proceedings of the 55th Annual Meeting of the Orthopaedic Research Society, Las Vegas, NV, USA, 2009.


Mylona E.
Cancer cell migration: substrate mechanics and intracellular mechanisms. Proceedings of the American Society of Cell Biology Annual Meeting, p.81, 2008.

Mylona E.
Cancer cell mechanotaxis and intracellular mechanisms. Proceedings of the American Society for Matrix Biology Biennial Meeting, 2008.

Mylona E.
, D. Manoussaki, and F. Jetzek. Substrate rigidity regulates multiple responses of tumor cells. Proceedings of the American Society for Cell Biology & European Cytoskeleton Forum Proceedings, p. 23, 2007.

Mylona, E.,
T.S. Mills, and G.K. Pavlath. CD44 regulates multiple steps in myogenesis. Mol. Biol. Cell 15(Suppl S): 2217, 2004.  

Mylona, E., T.J. McLoughlin, T. Hornberger, K.A. Esser. Muscle inflammatory cell concentrations following electrically stimulated contraction. FASEB J 16(5): A1138, 2002.

Peterson, J.M., T.A. Trappe, E. Mylona, F. White, C.P. Lambert, W.J. Evans, and F.X. Pizza. Ibuprofen and acetaminophen: Effect on muscle inflammation following eccentric contractions. FASEB J 16(5): A1139, 2002.

Anning, J.H., A.L. Morgan, P.G. Brolinson, P.M. Arnos, E. Mylona, and C. Wilkins. Influence of running and cycling on hydrostatic and oncotic forces associated with plasma volume shifts. Med. Sci. Sports & Exer. 34(5): S113, 2002.

Tsivitse, S.K., S.J. McGregor, J.M. Peterson, T.J. McLoughlin, E. Mylona, and F.X. Pizza. Muscle inflammation following down-hill running. Med Sci Sports Exer. 33(5): S120, 2001.

Kolasinski, S., T.J. McLoughlin, E. Mylona, S.K. Tsivitse, and F.X. Pizza. Effect of ischemic preconditioning on contraction-induced skeletal muscle injury. Med. Sci. Sports Exer. 33(5): S122, 2001.

Mylona, E., P.M. Arnos, J.H. Anning, S.A. Albers, A.L. Morgan, and F.F. Andres. Hemodynamic responses to moderate swimming and running during exercise and recovery. Med. Sci. Sports Exer. 31(5): S57, 1999.

Fahlman, M., E. Mylona, A.L. Morgan, D.J. Boardley, and S.K. Tsivitse. S-IgA following a single bout of exercise: Effects of fitness level and ambient temperature. Med. Sci. Sports Exer. 31(5): S61, 1999.

Braun, W.A., M.G. Flynn, D. Jacks, T. McLoughlin, J. Sowash, C. Lambert, E. Mylona, and M. Hansen. Effect of indomethacin on NK activity of PBMC. Med. Sci. Sports Exer. 31(5): S61, 1999.

Anning, J.H., C. Armstong, E. Mylona, S. Norkus, R. Sterner, and F. Andres. Physiological responses during cardiovascular kickboxing: a pilot study. Med. Sci. Sports Exer. 31(5): S110, 1999.

Arnos, P.M., E. Mylona, J.H. Anning, C. Armstrong, and F.F. Andres. Muscle activation patterns during total-body steady-state exercise. Med. Sci. Sports Exer. 31(5): S193, 1999.

Lambert, C.P., M.G. Flynn, W.A. Braun, and E. Mylona. The influence of acute submaximal exercise on suppressor cell function in healthy men. Med. Sci. Sports Exer. 30(5): S19, 1998.

Flynn, M.G., W.A. Braun, J. Armstrong, C.P. Lambert, D. Jacks, J. Yates, and E. Mylona. Effect of oral chondroitin sulfate supplements on muscle soreness, creatine kinase, and markers of inflammation. Med. Sci. Sports Exer. 30(5): S103, 1998.

Braun, W.A., M.G. Flynn, D. Jacks, T. McLoughlin, J. Sowash, C.P. Lambert, E. Mylona, and M. Hansen. Mechanisms of post-exercise NK suppression. Med. Sci. Sports Exer. 30(5): S175, 1998.

E. Mylona, D. Grekinis, P. Antoniou, N. Sofiadis, and S. Tokmakidis. Effects of heredity on hemodynamics of pre-adolescent swimmers during maximal exercise and recovery. Exercise and Society, 1996.


                                          Top CONFERENCE PRESENTATIONS



Mylona E., Alexopoulos L.G., Chairakaki K., Melas I. Substrate rigidity alters the secreted protein profile and chemotaxis response of fibrosarcoma cells. 444th Wilhelm and Else Heraeus Seminar on Cell Mechanics and 3rd European Meeting on Cell Mechanics, Physikzentrum, Bad Honnef, GERMANY ,  October, 2009.


Mylona E. Cancer cell mechanotaxis and mechanisms, Cell Biomechanics Wrokshop, Heraklion, HELLAS, 2009.

Dailiana, ZH; E. Mylona, X. Trepat, M.G. Lagoudakis, and M. Ioannou. Primary human osteosarcoma cell responses to alterations in substrate rigidity. 55th Annual Meeting of the Orthopaedic Research Society, Las Vegas, NV, USA, 2009.

Mylona E. Cancer cell migration: substrate mechanics and intracellular mechanisms. Proceedings of the 48th American Society of Cell Biology Annual Meeting, San Francisco, CA, USA, 2008.

Mylona E.
Cancer cell mechanotaxis and intracellular mechanisms. Proceedings of the American Society for Matrix Biology Biennial Meeting, San Diego, CA, USA, 2008.


Mylona E., Z.H. Dailiana, X. Trepat, and M.G. Lagoudakis. Substrate rigidity dictates phenotype, survival, and mechanics of primary human osteosarcoma cells, 6th European Symposium on Biomedical Engineering Symposium, Chania, Crete, HELLAS, 2008.


Manoussaki D. and E. Mylona. Characterizing cancer cell response, CancerSim2008: Euroconference on Modeling and Simulation of Cancer Growth and Therapy, Torino, ITALY, 2008.


Jetzek F., E. Mylona, and D. Manoussaki. Prediction of potential locations of focal adhesions on the contour of adherent cells, Fifth IEEE International Symposium on Biomedical Imaging, Paris, FRANCE, 2008.

Jetzek F., E. Mylona, and D. Manoussaki. Does nucleus morphology in adherent cells correlate with the spatial distribution of focal adhesions? MCRTN Summer Meeting
2007, Dundee, UK, 2007.

Mylona E., D. Manoussaki, and F. Jetzek. Substrate Rigidity Regulates Multiple Responses of Tumor Cells. American Society for Cell Biology & European Cytoskeleton Forum Summer Meeting, Dijon, FRANCE, 2007.

Mylona, E
., T.S. Mills, and G.K. Pavlath. CD44 controls multiple steps in myogenesis. Annual Conference of the American Society for Cell Biology, Washington D.C., USA, 2004.

Mylona, E., S.K. Tsivitse, J.M. Peterson, and F.X. Pizza. “Myotube-derived neutrophil chemoattractants: Effects of mechanical strain and injury”. Experimental Biology - Annual Meeting of the American Physiological Society, San Diego, USA, 2003.

Mylona, E., T.J. McLoughlin, T. Hornberger, K. Esser, and F.X. Pizza. Muscle inflammatory cell concentrations following electrically stimulated contractions. Experimental Biology - Annual Meeting of the American Physiological Society, New Orleans, USA, 2002.

Peterson, J.M, T.A. Trappe, E. Mylona, F.White, C.P. Lambert, W.J. Evans, and F.X. Pizza. Ibuprofen and acetaminophen: Effect on muscle inflammation following eccentric contractions. Experimental Biology - Annual Meeting of the American Physiological Society, New Orleans, USA, 2002.

Anning, J.H., A.L. Morgan, P.G. Brolinson, P.M. Arnos, E. Mylona, and C. Wilkins. Influence of running and cycling on hydrostatic and oncotic forces associated with plasma volume shifts. Annual Meeting of the American College of Sports Medicine, Saint Louis, USA, 2002.

Mylona, E., T.J. McLoughlin, T. Hornberger, K. Esser, and F.X. Pizza. Contraction-specific changes in inflammatory cells of rodent skeletal muscle. Regional (Midwest) Meeting of the American College of Sports Medicine, Columbus, OH, USA, 2001.

Mylona, E., P.M. Arnos, J.H. Anning, S.A. Albers, A.L. Morgan, and F.F. Andres. Hemodynamic responses to moderate swimming and running during exercise and recovery. Annual Meeting of the American College of Sports Medicine, Seattle, WA, USA, 1999.

Anning, J.H., C. Armstong, E. Mylona, S. Norkus, R. Sterner, and F. Andres. Physiological responses during cardiovascular kickboxing: a pilot study. Annual Meeting of the American College of Sports Medicine, Seattle, WA, USA, 1999.

Arnos, P.M., E. Mylona, J.H. Anning, C. Armstrong, and F.F. Andres. Muscle activation patterns during total-body steady-state exercise. Annual Meeting of the American College of Sports Medicine, Seattle, WA, USA, 1999.

Braun, W.A., M.G. Flynn, D. Jacks, T. McLoughlin, J. Sowash, C. Lambert, E. Mylona, and M. Hansen. Effect of Indomethacin on NK activity of PBMC. Annual Meeting of the American College of Sports Medicine, Seattle, WA, USA, 1999.

Lambert, C.P., M.G. Flynn, W.A. Braun, and E. Mylona. The influence of acute submaximal exercise on suppressor cell function in healthy men. Annual Meeting of the American College of Sports Medicine, Orlando, FL, USA,1998.

Flynn, M.G., W.A. Braun, J. Armstrong, C.P. Lambert, D. Jacks, J. Yates, and E. Mylona. Effect of oral chondroitin sulfate supplements on muscle soreness, creatine kinase, and markers of inflammation. Annual Meeting of the American College of Sports Medicine, Orlando, FL, USA, 1998.

Braun, W.A., M.G. Flynn, D. Jacks, T. McLoughlin, J. Sowash, C.P. Lambert, E. Mylona, and M. Hansen. Mechanisms of post-exercise NK suppression. Annual Meeting of the American College of Sports Medicine, Orlando, FL, USA, 1998.

E. Mylona, D. Grekinis, P. Antoniou, N. Sofiadis, and S. Tokmakidis. Effects of heredity on hemodynamics of pre-adolescent swimmers during maximal exercise and recovery. International Congress on Physical Education and Exercise Science, Komotini, GREECE, 1996.


                                       
PROFESSIONAL ACTIVITIES



  • Reviewer for the Journal of Sports Sciences

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PROFESSIONAL MEMBERSHIPS






Last update: February, 2011